Glucose-Responsive Insulin Delivery
Bio- and environment-responsive nanomaterials and intelligent drug delivery systems are being developed for closed-loop drug delivery, such as glucose-responsive insulin delivery, and for site-specific and targeted drug delivery.
We have synthesized stimulus-responsive nano-hydrogels and bio-inorganic hybrid nanocomposite materials and studied their physicochemical properties and interactions with proteins, cells and tissues. We have devised an "intelligent" membrane platform technology that enables alteration of release rate of drugs, protein and polypeptides in response to various physical, chemical and biochemical triggers. We are now developing this platform technology into medical devices and pharmaceutical products for the treatment of Diabetes.
Advanced Functional Materials 2011, 21(1):73-82
Advanced Functional Materials 2010, 20(9):1404-1412
We have synthesized stimulus-responsive nano-hydrogels and bio-inorganic hybrid nanocomposite materials and studied their physicochemical properties and interactions with proteins, cells and tissues. We have devised an "intelligent" membrane platform technology that enables alteration of release rate of drugs, protein and polypeptides in response to various physical, chemical and biochemical triggers. We are now developing this platform technology into medical devices and pharmaceutical products for the treatment of Diabetes.
Advanced Functional Materials 2011, 21(1):73-82
Advanced Functional Materials 2010, 20(9):1404-1412